• Premature menopause
• Genetic abnormality
• Carriers of a genetic disorder
• Poor ovarian response to hormonal stimulation
• Absence of the ovaries
• Ovarian failure due to chemotherapy and/or radiation treatment

What Kind of People Donate Eggs?
Donors are anonymous unless the recipient chooses a family member or friend to be the oocyte donor. In both cases the donors undergo rigorous screening.

Potential egg donors come forward voluntarily for different reasons.
The donors must undergo extensive screening to evaluate whether or not they will be suitable for egg donation. Donors must be between the ages of 21 and 31. They are asked to complete a detailed questionnaire, which is reviewed by our staff. If the questionnaire is favorable then they are interviewed. A potential donor's medical history, both present and past as well as family history is taken into careful consideration. Donors undergo a rigorous physical examination and an assessment by both a clinical psychologist and geneticist. The psychological evaluation ensures that the donor will be well adjusted without any underlying psychological problems. Potential donors are asked to complete a standardized psychological test. A careful genetic history is taken by a trained geneticist in order to ensure there are no hereditable disorders in the family. If there is any suspicion due to particular backgrounds, they are appropriately genetically screened. All oocyte donors are evaluated for cystic fibrosis, which is the most common hereditary disease in the United States.

All donors are carefully screened for sexually transmittable diseases and any other potential infectious disease. Also performed are a drug screen, cervical cultures for sexually transmittable diseases, hepatitis, HIV and syphilis. Ovarian reserve is assessed hormonally.

The donors are anonymous and the potential recipient is not disclosed to the donor, nor are the results of their cycle. Even though the program is anonymous, the recipient has available to them the donor's profile, psychological evaluation and genetic evaluation. This allows the potential recipient to have available at their fingertips sufficient information to make an informed decision regarding their potential donor.


How Are Donors and Recipients Matched?
Recipients complete a profile form listing specifics attributes they want from the donor. In addition to the specific attributes requested, physical characteristics are also used in matching. Our team plays a vital role in assisting the coordinator in making appropriate matches with the donor. All matches are confidential.

Synchronization of Cycles
The cornerstone of egg donation is the synchronization of the ovarian cycles of both the egg donor and the recipient. This ensures that the embryos are placed in the recipient's womb at the optimal time for implantation.

When both the donor and the recipient are regulated, the donor starts the fertility medication (gonadotropin injections) to stimulate her ovaries to produce eggs. The recipient will start her estrogen replacement prior to the donor starting her medications.

While the donor is receiving the fertility medication to mature follicles to provide eggs, the estrogen the recipient is taking will prepare the lining of her uterus so it will be able to receive the embryos.

The eggs are fertilized in the manner that offers the best chance of success. The method of fertilization (conventional versus ICSI) is agreed upon by the couple prior to insemination taking place.

Three or five days after the retrieval, the embryos are placed in the recipient's uterus. The number of embryos transferred depends on the age of the donor and the quality of the embryos on the day of the transfer. The decision on the number of embryos to transfer is an important one with the goal of maximizing the probability of pregnancy without a high risk of multiple gestations. After the embryo transfer the recipient will continue taking the hormones and a pregnancy test will be performed in approximately two weeks. If there is a surplus of embryos and they can be cryopreserved, the couple is offered additional chances of conception. Since the woman does not need to undergo gonadotropin stimulation again, the cost is greatly reduced.

What Guarantees Are There with the Donor?
Donors come forward voluntarily. They can be either anonymous or are known. They are well-motivated and usually complete the treatment for egg donation. It is, however, completely within their rights to withdraw from treatment at any given time until egg retrieval.

There may be a rare occasion when the donor does not produce enough follicles or stimulates too quickly. In either of these instances, the treatment cycle may be canceled due to poor donor response or due to high risk of ovarian hyperstimulation syndrome.